European Journal of Molecular & Clinical Medicine

Abstract

In the medical literature, AUB is described as an episode of abnormal uterine bleeding that is not due to any clinically evident organic, systemic, or iatrogenic cause (Pelvic pathology, e.g. tumor, inflammation or pregnancys excluded). ¹ Although the prevalence varies widely, a 10-percent incidence rate among new patients entering the outpatient clinic appears reasonable. The bleeding may be abnormal in terms of frequency, volume, or duration, or it may be a mix of any of these characteristics. Because the diagnosis is dependent on the exclusion of a 'organic lesion,' the incidence varies depending on the level of care and facilities available to rule out such a lesion. AUB is currently defined as a condition characterized by abnormal uterine bleeding following an ovulation as a result of hypothalamo-pituitary-ovarian axis malfunction (endocrine origin).