ASSESSMENT OF CARDIOVASCULAR MORBIDITIES IN PREDIABETIC INDIVIDUALS - A COMPARATIVE CROSS SECTIONAL STUDY
European Journal of Molecular & Clinical Medicine,
2023, Volume 10, Issue 1, Pages 1252-1258
AbstractBackground: Prediabetes is a disorder of glucose homeostasis characterized by impaired glucose tolerance or impaired fasting glucose. Prediabetes is associated with structural RA and RV changes, and impaired RV systolic and diastolic function, independent of cardiovascular risk factors. Prediabetics are at increased risk of developing type 2 DM. Present study was aimed to assess cardiovascular morbidities in prediabetic individuals.
Material & Method: This hospital based analytical comparative study was conducted among the individuals attending the medicine OPD of Aarupadai Veedu Medical College & Hospital aged more than 18 yrs with impaired fasting glucose and healthy controls. Comparison between Venous Blood Glucose Levels(Fasting, Impaired Glucose Tolerance) and changes in Electrocardiography, Echocardiography were done.Patients with pre-diagnosed cardiac disease, pancreatic disease, chronic kidney disease, thyroid disorders, dyslipidaemia, obese persons and pregnant women were excluded from the study. All the collected data were analysed using SPSS v21 operating on windows 10, with p<0.05 considered statistically significant.
Results: Total 252 participants included among them assessment of the cardiovascular morbidities were done, There were significant higher incidence of ECG and 2D ECHO changes among prediabetic compared to the controls. The ECG and 2D ECHO abnormal findings were seen in 71.5% among the prediabetic cases and zero % in controls.(p<0.05). Mean weight of cases was significantly higher than controls, BMI was significantly higher in cases compared to controls. (p<0.05)
Conclusion: Present study concludes that there is higher incidence of cardiovascular morbidities among the Prediabetes individuals compared with normoglycemic healthy individuals.
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