European Journal of Molecular & Clinical Medicine

Abstract

The aim of this study is to assess various histo-pathological changes in knee joint cartilage in end stage osteo-arthritis. Of the various clinical scoring systems available, the Oxford Knee score is considered. The questionaire, specifically designed for patient undergoing total knee replacement, hence most appropriate for this study. It is a short, practical, reliable, valid and sensitive to clinically important changes over time and is now widely applied and accepted model.
Result: Mean score value of oxford knee is 25.69.
Conclusion: In recent years, our perception of OA has changed significantly. It is increasing obvious that it is difficult to distinguish between changes in the joints occasioned by age and those of true OA recalling that both are interrelated. Arguably, it is it is even difficult to know what OA actually is or how to diagnose it. The disease, if indeed, is one disease is no longer seen as wear and tear disorder or one in which cartilage failure and wear produce joint disruption.