European Journal of Molecular & Clinical Medicine

Abstract

Diabetes is a “metabolic disorder of multiple aetiologies characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both “is defined as diabetes mellitus by WHO.¹ According to several studies has observed that the number of cases of diabetes worldwide in the year 2000 among adults at around 171 million, but the number of cases of diabetes mellitus is likely to rise around 366 million by the year 2030. So the present study is done to observe the correlation serum zinc levels with HbA1C levels and microalbuminuria. A cross sectional observational study is done on 70 patients divided into2 groups cases-with complications and controls-without complications who presented to the department of General Medicine, VMMC, Karaikal, Pondicherry with diabetes mellitus for duration of 6 months. All cases of type 2 diabetes mellitus patients attending general medicine Outpatients with complications are included in study. The mean HbA1C value of cases is 7.823% with a standard deviation of 1.29% and the mean HbA1C of controls is 5.83% with a standard deviation of0.53%, p-value is <0.005 which is statistically significant. In cases urinary albumin excretion was 90.5±63 mg/dl and in control group it is 86.5±62mg/dl, p-value is <.005 which is statistically significant indicating that in coastal areas there are elevated levels of zinc despite of poor glycaemic control.