Microbial strain pattern in blood and urine and their sensitivity to drugs with patients on mechanical ventilation
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 7, Pages 9732-9738
AbstractPatients admitted to intensive care units have been found to experience HAIs at a rate 5-10 times higher than patients treated to normal wards. The present study was conducted to find microbial strain pattern in blood and urine and their sensitivity to drugs with patients on mechanical ventilation.
Materials & Methods: 100 patients between the age of 18 to 65 years on mechanical ventilation of both genders in the department of Medicine, Gandhi Medical College and associated Hamidia Hospital, Bhopal were recruited. Parameters such as TLCs, neutrophil counts and lymphocyte counts were recorded. Micro-organism in Blood and urine was calculated. Antibiotic susceptibility pattern was also recorded.
Results: Majority of the patients in our study was male (72%) as compared to female (28%). The mean age of the study participants was 50.60+19.22 years. The mean TLCs, Neutrophil counts and Lymphocyte counts were 9411+3522, 63.79+4.6 and 33.11+4.86 respectively. The most common microorganism isolated from blood was MRSA (5%), acinetobacter (4%), citro (2%) and pseudomonas (1%). In terms of antibiotic sensitivity of blood sample samples, majority of the patients had bacteriological profile resistant to ciprofloxacin (80%), penicillin (80%), teicoplanin (80%), vancomycin (80%), Amikacin (80%)cefozitin (70%), cotrimoxazole (60%), Clindamycin (50%), doxycyclin (50%), Linezolid (50%), Amoxiclav (50%) and piptaz (50%). The most common microorganisms isolated from urine were E coli (6%), enterococcus (4%), MRSA (2%) klebsiella sp. (2%), citro (2%) and acinetobacter (1%). Majority of the bacterial isolates from urine sample were resistant to ampicillin (58.8%), cefotaxime (58.8%), ceftriaxone (52.9%), ciprofloxacin (52.9%), ceftazidime (52.9%), cefepime (47.1%) and penicillin (35.3%), Linezolid (35.3%), gentamicin (35.3%) and cotrimoxazole (35.3%), Clindamycin (35.3%), ciprofloxacin (35.3%), azithromycin (35.3%) and cefozitin (35.3%).
Conclusion: The most common microorganisms isolated from urine were E coli. Majority of the bacterial isolates from urine sample were resistant to ampicillin.
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