European Journal of Molecular & Clinical Medicine

Abstract

Type 2 diabetes mellitus is becoming a global epidemic affecting the Asian population, India being the capital of diabetes. Diabetes type 2 is associated with mortality from cardiovascular disease , micro vascular complications affecting the eyes, kidneys, nerves as well as with significant co morbidities including cancer,infections.If left untreated it leads to micro vascular complications like blindness, kidney failure, foot ulcerations, amputations. Treatment of such complications of diabetes mellitus type 2 is challenging at an institutional level as well as individual level.
Most of the challenges include prolonged therapy regular follow-up, cost efficacy of the treatment , availability of health care facility, etc. though it is challenging to implement, timely management of diabetes has been proven to reduce its complications.
   Diabetic foot ulcer represents a formidable clinical problem. successful treatment requires a thorough understanding of the pathological process, surgical debridement of  devitalized tissue and updating various modalities of treatment . Failure to recognize the cause, pathology and associated infectious process may lead to devastating consequences, like amputation and death.The diabetic foot can be defined as a syndrome in which neuropathy, angiopathy and infection coexist leading to tissue breakdown resulting in mobidity and possible amputation.