European Journal of Molecular & Clinical Medicine

Abstract

Recent studies have also revealed that vitamin D may help protect against a number of chronic diseases, including the risk of developing diabetes, cardiovascular disease, lung disease, and other chronic illnesses, such as systemic infections. The growing body of knowledge around vitamin D has started to suggest possible associations between sepsis and vitamin D insufficiency. The understanding of the relationships between these disorders is still in its infancy.
Aim: The aim of the study was to assess the role of Vitamin D deficiency as a potential risk factor for sepsis development and correlation with qSOFA score in patient admitted to Medical ICU in MMCH, Solan.
Methodology: This was a cross sectional study conducted among 120 patients diagnosed with Sepsis presenting to the Medical ICU.
Results: The mean age of the study participants was 55.87 ± 13.07. Majority of the study participants were males. The prevalence of diabetes mellitus and hypertension were 45.8% and 40% respectively. Mortality was seen among 3.3% were alive and dead respectively. 100% of the study participants with sepsis with qSOFA score of more than 2, had Vitamin D deficiency and the mean Vitamin D level was 12.21 ± 5.38. The Vitamin D level was significantly lower among those who died than those who are alive (p=0.019).
Conclusion: 100% of the sepsis patients had Vitamin D deficiency in the present study. It has been shown that this has a detrimental effect on inpatient morbidity and death. This emphasises how crucial it is for the general public to have enough vitamin D supplements.