Influence of pharmaceuticals on the development of obesity
European Journal of Molecular & Clinical Medicine,
2023, Volume 10, Issue 1, Pages 4122-4126
AbstractUkraine has been at war for almost a year. This cannot but affect the mental health of the nation. Anxiety-depressive disorders (ADD) and other manifestations of psychological health disorders are increasingly registered among our citizens. At the same time, it is well known that certain groups of antipsychotic and antidepressant drugs have an impact on body weight (BW).
Material and methods:By design, the study involved 154 patients aged 18 to 55 years who were not diagnosed with obesity prior to the war. The study was conducted at the Department of Family Medicine and Polyclinic Therapy of the Odesa National Medical University. By design, patients were divided into three groups: 1 group - patients who received antipsychotics for the treatment of ADD; 2 group - patients who received antidepressants and group 3 - patients who did not receive pharmacological treatment of ADD.
Results: Study wasshowed that 53.90% of patients had depression of varying degrees, 46.10% of patients had anxiety. The general tendency of increasing the patient's BW corresponds to the global practice. Thus, the greatest increase in BW was observed in 38 patients (24.66%) who took antipsychotics, especially Clozapine, Olazapine or Haloperidol. These patients showed an increase, sometimes even up to 10-12 kg over 6 months of treatment.
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