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“Molecular detection of colistin resistance among Multidrug Resistant (MDR) Pseudomonas aeruginosa”

    Authors

    • Angel Roy 1
    • Dr Tejashree .A 2
    • Dr Satya Sai.B 3
    • Dr Sujatha S.R 4
    • Dr Krishna Karthik. M.V.S 5

    1 MSc Post graduate, Dept of Microbiology, JSS Medical College, JSSAHER, Mysuru.

    2 Professor and Head, Dept of Microbiology, JSS Medical College, JSSAHER, Mysuru.

    3 Tutor, Dept of Microbiology, JSS Medical College, JSSAHER, Mysuru.

    4 Senior Resident, Dept of Microbiology, JSS Medical College, JSSAHER, Mysuru.

    5 Tutor, Dept of Microbiology, JSS Medical College, JSSAHER, Mysuru

,

Document Type : Research Article

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Abstract

ABSTRACT: P.aeruginosa is a common cause of hospital-acquired infections, and it's especially troublesome in intensive care units.Pseudomonas aeruginosa shows intrinsic resistance to a number of antibiotics. Treatment of infection has become a challenge as number of antibiotic resistant strains is on the rise. In general, Pseudomonas aeruginosa resist antibiotic attack by intrinsic, adaptive, and acquired resistance mechanisms. Resistance can be acquired by transfer of genes coding resistance carried on plasmids, transposons, integrons or prophages or through mutational changes. Now, worldwide emergence of colistin resistance has also occurred. Colistin resistance in Pseudomonas aeruginosa can be caused by chromosomal mutations as well as by the acquisition of plasmid-carrying determinants, primarily mcr-1. Hence, this current study was aimed to detect the presence of mcr genes among MDR P.aeruginosa isolated from various clinical specimens.

Keywords

  • Keywords: P.aeruginosa
  • intrinsic resistance
  • colistin resistance
  • mcr genes
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European Journal of Molecular & Clinical Medicine
Volume 10, Issue 1 - Issue Serial Number 1
January 2023
Page 4236-4242
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APA

Roy, A., .A, D. T., Sai.B, D. S., S.R, D. S., & M.V.S, D. K. K. (2023). “Molecular detection of colistin resistance among Multidrug Resistant (MDR) Pseudomonas aeruginosa”. European Journal of Molecular & Clinical Medicine, 10(1), 4236-4242.

MLA

Angel Roy; Dr Tejashree .A; Dr Satya Sai.B; Dr Sujatha S.R; Dr Krishna Karthik. M.V.S. "“Molecular detection of colistin resistance among Multidrug Resistant (MDR) Pseudomonas aeruginosa”". European Journal of Molecular & Clinical Medicine, 10, 1, 2023, 4236-4242.

HARVARD

Roy, A., .A, D. T., Sai.B, D. S., S.R, D. S., M.V.S, D. K. K. (2023). '“Molecular detection of colistin resistance among Multidrug Resistant (MDR) Pseudomonas aeruginosa”', European Journal of Molecular & Clinical Medicine, 10(1), pp. 4236-4242.

VANCOUVER

Roy, A., .A, D. T., Sai.B, D. S., S.R, D. S., M.V.S, D. K. K. “Molecular detection of colistin resistance among Multidrug Resistant (MDR) Pseudomonas aeruginosa”. European Journal of Molecular & Clinical Medicine, 2023; 10(1): 4236-4242.

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