European Journal of Molecular & Clinical Medicine

Abstract

Each patient was randomly assigned to one of the two groups of 30 patients each using random table. Group A Patients who received instillation of 20cc of 0.5% Bupivacaine diluted to 40cc with NS intraperitoneally, a total of 40cc. Group B patients who received instillation of 20cc Bupivacaine 0.5% diluted till 40cc with NS with Dexmedetomidine 50mcgs intraperitoneally, a total of 40cc. The patient was blind to the drug injected. All patients underwent thorough medical evaluation and routine lab investigations a day prior to surgery Result; In the present study mean age of Bupivacaine group was 26 and Bupivacaine with Dexmedetomidine study group was 25.65.There was statistically significant difference between two groups of patients in terms of pulse rate and , Systolic BP all the time.The mean VAS as per data, the gradual increase of the VAS scores is comparable, and showed statistical significance between two groups. Comparisons of pain between two groups by Visual Analogue Scale scores were statistically significant at all time point except 6,8 and 24 hour.This study also showed that Bupivacaine provided adequate analgesia for the first  1 to 2 hours when compared to Bupivacaine+Dexmed, which provided adequate analgesia for about 4 to 6 hours.  Conclusion: We concluded that the administration of the intraperitoneal local anaesthetic agent, Bupivacaine in combination with dexmedetomidine can effectively reduce the need for prescribing postoperative analgesic drugs as well as decrease postoperative pain severity in minimal surgery..