Histopathological Spectrum Of Ovarian Neoplasms: A 15 Months Prospective Study At A Tertiary Care Centre Of Rajasthan
European Journal of Molecular & Clinical Medicine,
2023, Volume 10, Issue 1, Pages 4760-4771
Abstract
Background: The ovaries are reproductive organ, the source of female fertility, and at the same time, the origin of many of the most complex as well as lethal neoplasms. Worldwide, ovarian cancer is the most frequent cause of death from gynecological cancers.Aim & Objectives: To study the histopathological spectrum of ovarian tumors, their clinical presentation and age distribution.
Materials & Methods: A prospective study was conducted over a duration of 15 months (April 2021 to June 2022) in the Department of Pathology, SMS Medical College, Jaipur, Rajasthan. A total of 134 cases were studied and analyzed for age, histopathological findings and clinical presentations.
Results: Out of 134 cases of ovarian neoplasms, 84 cases (62.7%) were benign, 6 cases (4.4%) were borderline, 44 cases (32.8%) were malignant. Among the histologic subtypes, 77 cases (57.5%) were of surface epithelial histotype, 32 cases (23.9%) were of germ cell histotype, 23 cases (17.2%) were sex-cord stromal tumors and 1 case each of metastatic and miscellaneous tumors were observed. Tumors were seen over age range of 6-82 years with maximum number of cases in 3rd to 5th decade (68.7%). Most of the cases presented with chief complaint of abdominal pain and lump abdomen, seen in 77.6% and 66.4% cases respectively.
Conclusion: Surface epithelial tumors are the most common variant followed by germ cell tumors and sex-cord stromal tumors. Correlation among clinical details, radiology, serology and gross morphology gives important clue for proper histopathological diagnosis, thereby helping the gynecologists in initiating proper and timely management of the patient.
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