European Journal of Molecular & Clinical Medicine

Abstract

Introduction: Patients undergoing cesarean sections frequently have hypotension following spinal anesthesia; maternal hypotension occurs 60%–70% of the time. By giving intravenous fluid boluses, hypotension brought on by spinal anesthesia can be treated or avoided. The purpose of this study was to assess the efficacy of crystalloid fluid preloading and co-loading in reducing the occurrence of hypotension following spinal anesthesia in cesarean delivery.
Method: There were 54 participants total who took part in this investigation. Subjects chosen through successive sampling who met the inclusion criteria for elective cesarean sections under spinal anesthesia were gravida individuals between the ages of 15 and 41 with an ASA 1 or ASA 2 physical condition. Three groups- the preloading group, the co-loading group, and the control group- were formed from the participants. Mean arterial pressure (MAP), pulse rates, and systolic and diastolic blood pressure are assessed in resting conditions and 2, 3, 5, 7, 9, 11, 13, 15, and 25 minutes following spinal anesthesia. The Repeated Measured Multivariate Analysis of Variance (MANOVA) test was used in the statistical analysis to see how the three groups of patients differed in terms of several hemodynamic parameters. The variations in hemodynamic parameters between each group were compared using the Bonferonni post hoc test.
Results: Results of the Bonferroni post hoc test revealed significant differences in the decline in systolic, diastolic, and MAP blood pressure between the co-loading group with the preloading group and the control group (P < 0.002); the co-loading group experienced the lowest decline.
Conclusion: Compared to the preloading and control groups, crystalloid fluid co-loading dramatically reduced the incidence of hypotension following spinal anesthesia in cesarean delivery.