European Journal of Molecular & Clinical Medicine

Abstract

Pulmonary tuberculosis is respiratory infection caused by M.tuberculosis bacilli which occur via
aerosol. First line drugs used in the treatment of TB are Isoniazid (H), Rifampicin (R),
Pyrazinamide (Z) and Ethambutol (E). Use of multidrug regimens has been associated with
increased incidence of adverse drug reactions, involving all the major organs. However the
frequency of occurrence of ADRs to ATT involving major organs are not well known, so in this
study we tried to find out the most commonly affected organ due to ATT.