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  2. Volume 10, Issue 2
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Online ISSN: 2515-8260

Volume10, Issue2

Assessment of left ventricular filling pressure and its correlation with severity of chronic kidney disease

    Siddhartha Rout, Mohammed Mudassir Ali, Amritarnav Rout, Mohammed Asif Muzafer Iqubal

European Journal of Molecular & Clinical Medicine, 2023, Volume 10, Issue 2, Pages 1098-1103

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Abstract

Chronic kidney disease (CKD) is a common health problem worldwide. Cardiovascular disease is the most common cause of morbidity and mortality in CKD. In CKD patients, use of Echocardiography can help in establishing a diagnosis of acute decompensated heart failure. Present study was aimed to assessment of left ventricular filling pressure and its correlation with severity of chronic kidney disease. Material and Methods: Present study was single-center, prospective, observational study, conducted patients aged >18 years, either gender, diagnosed cases of CKD as per KIDGO criteria underwent resting 2-D transthoracic echocardiography. Results: In present study, 80 cases of CKD underwent 2-D transthoracic echocardiography evaluation. Majority were from 50-59 years age group (53.75 %), male (66.75 %). In present study majority were from CKD stage 2 (53.75 %) followed by CKD stage 3 (28.75 %), CKD stage 4 (22.5 %) & CKD stage 5 (13.75 %). Among study patients, 45 patients (56.25 %) had normal LVFP, while 27 patients (33.75 %) had 9-13 LVFP & increase in LVFP (> 13) was noted in 8 patients (10 %).  Mean value of LVFP in CKD stage 2 was 8.68 ± 2.15, mean LVFP in CKD stage 3 was 10.34 ± 2.64, mean LVFP in CKD stage 4 was 12.92 ± 3.84 & mean LVFP in CKD stage 5 was 13.46 ± 3.23. We noted statistically significant association between increase in stage of CKD with progressive rise in mean LVFP value. Conclusion: The increase in left ventricular filling pressure is directly proportional to the CKD stage i.e., severity of renal failure. 
Chronic kidney disease (CKD) is a common health problem worldwide. Cardiovascular disease is the most common cause of morbidity and mortality in CKD. In CKD patients, use of Echocardiography can help in establishing a diagnosis of acute decompensated heart failure. Present study was aimed to assessment of left ventricular filling pressure and its correlation with severity of chronic kidney disease. Material and Methods: Present study was single-center, prospective, observational study, conducted patients aged >18 years, either gender, diagnosed cases of CKD as per KIDGO criteria underwent resting 2-D transthoracic echocardiography. Results: In present study, 80 cases of CKD underwent 2-D transthoracic echocardiography evaluation. Majority were from 50-59 years age group (53.75 %), male (66.75 %). In present study majority were from CKD stage 2 (53.75 %) followed by CKD stage 3 (28.75 %), CKD stage 4 (22.5 %) & CKD stage 5 (13.75 %). Among study patients, 45 patients (56.25 %) had normal LVFP, while 27 patients (33.75 %) had 9-13 LVFP & increase in LVFP (> 13) was noted in 8 patients (10 %).  Mean value of LVFP in CKD stage 2 was 8.68 ± 2.15, mean LVFP in CKD stage 3 was 10.34 ± 2.64, mean LVFP in CKD stage 4 was 12.92 ± 3.84 & mean LVFP in CKD stage 5 was 13.46 ± 3.23. We noted statistically significant association between increase in stage of CKD with progressive rise in mean LVFP value. Conclusion: The increase in left ventricular filling pressure is directly proportional to the CKD stage i.e., severity of renal failure. 
Keywords:
    left ventricular filling pressure CKD stage Diastolic dysfunction Echocardiography
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(2023). Assessment of left ventricular filling pressure and its correlation with severity of chronic kidney disease. European Journal of Molecular & Clinical Medicine, 10(2), 1098-1103.
Siddhartha Rout, Mohammed Mudassir Ali, Amritarnav Rout, Mohammed Asif Muzafer Iqubal. "Assessment of left ventricular filling pressure and its correlation with severity of chronic kidney disease". European Journal of Molecular & Clinical Medicine, 10, 2, 2023, 1098-1103.
(2023). 'Assessment of left ventricular filling pressure and its correlation with severity of chronic kidney disease', European Journal of Molecular & Clinical Medicine, 10(2), pp. 1098-1103.
Assessment of left ventricular filling pressure and its correlation with severity of chronic kidney disease. European Journal of Molecular & Clinical Medicine, 2023; 10(2): 1098-1103.
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