Assessment Of Hormone Receptor Status In Breast Carcinoma And Its Relation To Lymph Node Status
European Journal of Molecular & Clinical Medicine,
2023, Volume 10, Issue 1, Pages 5138-5141
AbstractBackground: The present study was undertaken for assessing hormone receptor status in breast carcinoma and its relation to lymph node status.
Materials & methods: 20 breast cancer patients were enrolled. Complete demographic and clinical details of all the patients were obtained. Patient and tumor characteristics of age, tumor size and number of nodes involved was recorded. Estrogen receptor (ER), progesterone receptor (PR) (positive and negative) were noted separately. All the necessary investigations were carried out (Core cut biopsy/FNAC). Intraoperative details were recorded in each patient. Histopathology examination of lymph nodes was done.
Results: Lymph node involvement was seen in 75 percent of the patients. PR positivity was seen in 50 percent of the patients while ER Positivity was seen in 45 percent of the patients. While assessing the correlation of lymph node status with PR and ER status, significant results were obtained. All the breast cancer patients with lymph node involvement were PR and ER positive.
Conclusion: Majority of the patients were diagnosed with breast cancer in their 40s. Most of the women in the younger age groups were estrogen receptor (ER) and progesterone receptor (PR).
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