European Journal of Molecular & Clinical Medicine

Abstract

Background: Clinical signs and symptoms of cutaneous vasculitis can vary greatly. It could be idiopathic or linked to a variety of illnesses, such as infections, medications, etc. Small vessel vasculitis (SVV) and medium vessel vasculitis both affect the skin (MVV). There are similarities between the characteristics of SVV and MVV. The histological characteristics and the clinical lesions may not always be related. The current study's objective was to assess the clinicopathological correlation and etiological variables in individuals with cutaneous vasculitis.
Methods:  All patients with clinical signs and symptoms that are suggestive of small vessel vasculitis, such as palpable purpura, infiltrated erythema, hemorrhagic vesicles and bulla, ulcers, infarcts, digital gangrene, erythematous plaques and nodules, urticaria, and livedoreticularis. Clinical evaluation: Extensive systemic and general evaluations were performed. The morphology of the skin lesion, its location, symmetry, pain, and diascopy were all thoroughly examined.
Results: Based on the inclusion and exclusion criteria n=30 cases with clinical features of cutaneous small vessel vasculitis were seen during the study period. Out of the total cases seen the common types were Henoch Schonlein purpura in n=12/30 (40%), Erythema nodosum leprosum n=7/30 (23.33%), small vessel vasculitis associated with collagen vascular disease n=6/30 (20%). The less common types were urticarial vasculitis n=1/30 (3.33%) septic vasculitis n=2/30 (66.66%), essential mixed cryoglobulinemia n=1/30 (3.33%) the details of the distribution between males and females.
Conclusion: The most frequent kind of cutaneous small vessel vasculitis identified in the current investigation was Henoch Schonlein purpura, followed by Erythema nodosum leprosum. Females tended to have cutaneous small vessel vasculitis more often. The majority of the cases were people under 40 years of age. Upper respiratory tract infection was the most prevalent causative factor. The clinical diagnosis of cutaneous small vessel vasculitis is based on the presence of non-thrombocytopenic purpura