European Journal of Molecular & Clinical Medicine

Abstract

To predict the risk factor for intra uterine growth retardation and preeclampsia in pregnant women with the help of uterine artery Doppler screening and associated indices (pulsatility index and diastolic notching) of sensitivity and specificity
Method: Prospective, Descriptive study uterine artery Doppler assessment was carried out at 12 to 14 weeks and 20 to 26 weeks gestation in unselected women with singleton as well as multiple pregnancies, attending for routine antenatal care in a primary care center. The Diastolic notching, pulsatility index (PI) and its relationship to preeclampsia as well as IUGR were evaluated at first and second trimester.
Results: Uterine artery diastolic notch detection had a sensitivity (preeclampsia=52% ; IUGR=18.92%) and a specificity (preeclampsia= 76.8 %; IUGR=66.27%) of in the first trimester whereas a sensitivity (preeclampsia=68% ; IUGR=27.03%) and a specificity (preeclampsia= 89.5%; IUGR=79.52%) in the mid trimester. The pulsatile index detection had a sensitivity of (preeclampsia= 48%; IUGR=35.14%)  and a specificity (preeclampsia=49.5% ; IUGR=43.37) of in the first trimester whereas a sensitivity (preeclampsia=40% ; IUGR=29.73%) of 40% and a specificity(preeclampsia= 55.59%; IUGR=50.60%)  of in the mid trimester.
Conclusion: Uterine artery Doppler sonography fulfill all the requirements for screening in prediction of pre-eclampsia and IUGR. Our results are comparable to the results of other studies.