European Journal of Molecular & Clinical Medicine

Abstract

Despite changing strategies, meconium staining of the amniotic fluid (MSAF) happens in approximately 10-15% of childbirth. MAS develops in approximately 4-10% of the infants born from a MSAF milieu. Of these neonates who develop MAS, one third require ventilatory support, 10% develops air leak and in spite of appropriate management strategies,5-10% of them have a fatal outcome. Of the babies who suffer persistent pulmonary hypertension of the newborn (PPHN) 5-6% are related to MAS2. As per sample size 70 cases have been studied. Their outcomes were assessed. Term> 37 weeks both inborn and outborn cases were included. Preterm< 37 weeks and babies with congenital malformation were excluded in this study.Out of 70 babies taken into the study, 60 were inborn & 10 were outborn. Mean birth weight was 2.8 Kg. 72.9% were delivered through LSCS and 17.1% through instrumental and 10% through NVD. There was mortality in 5.7% 47.2% were classified as severe MAS. Most common complication in MAS was HIE (15.7%) followed by sepsis (11.4%) and PPHN (8.6%). Most common radiological features was hyperinflation (41.4%) followed by Consolidation (30%).