European Journal of Molecular & Clinical Medicine

Abstract

This research study investigates the impact of ageing on the shape and size of Meissner’s corpuscles in the great toe of the human foot. By using histological sections of thick skin were taken from 53 samples of different age groups and five samples from the foetus. we have measured H&E-stained alternate sections of thick skin of different age groups. the Meissner’s corpuscles were measured by using ImageJ software. Results: The morphometric parameters, including ranges of horizontal length (48.07mm to 46.63mm), vertical length (102.42mm to 137.41mm), perimeter (267.02mm to 354.42mm), area (4131.24mm² to 5598.56mm²), capsule thickness (5.29mm to 10.79mm) and depth (9.2mm to 10.79mm). We did not find MC in foetal samples of a particular age group. We have also observed that the shape of the MC varies from oval, ellipsoid in shape, discoid, dumbbell shape, cylindrical, large oval shape, bean shape, inverted cone shape, triangular in shape, coiled spring shape, cone shape, and spindle in shape.