European Journal of Molecular & Clinical Medicine

Abstract

Introduction: Sevoflurane is one of the general anesthetic having  a  rapid  onset and offset of action. Hence anesthetist can control the depth of anesthesia rapidly. Intravenous propofol with rapid induction and  recovery  is a  popular  induction  agent nowadays for surgical anesthesia. Objectives: To compare the effect of sevoflurane and propofol for inducing anesthesia in short elective surgeries. Methods: The study was conducted at Government Medical College,Nizamabad,Telangana,India. Hundred patients prepared for elective short surgery were taken into the study. After pre-anesthetic medication, one group of patients were induced with : O2:N2O  (50:50)  +  Sevoflurane  3-4%  and the other group induced with:  O2:N20  (50:50)  +Propofol 3-5 mg/kg.Parameters like relavant intra-op details, ease of procedure, hemodynamic changes, recovery, and complication rate were compared between both groups.Results: Parameters like jaw opening, attempts for LMA and ease of insertion was comparable in both the groups . Time to loss of consciousness and time  to  LMA insertion was significantly shorter with Propofol. Mean pulse rate and MAP was significantly higher in Sevoflurane group.  Conclusion:  Inhaled Sevoflurane is better for LMA insertion and intra-operative hemodynamic profile during anesthesia was stable.Sevoflurane can be considered as an alternative induction agent when inhalational induction is required. We should keep in mind that  caution  still needs to be continued when sevoflurane is used.