European Journal of Molecular & Clinical Medicine

Abstract

The gallbladder is stimulated to contract and expel the bile in to
duodenum by the hormone cholecystokinin pancreozymin (CCK) produced by the
endocrine cells of the duodenal mucosa in response to food (Norman S. Williums, Bailey
and Loves, 25th edition). Aims and Objectives: Study of Clinical profile and factors
associated with Gall Stones at tertiary health care center. Methodology: This was a
cross-sectional study in the patients of Gall bladder disease in the department of
Surgery of a tertiary health care center during the year January 2016 to January 2017
so during one-year period there were 106 patients after written consent were included
into study. The data was presented in the Tabular form and expressed in the
percentages. Result: In our study we have seen that The majority of the patients were in
the age group of 40-50 were 30.19%, followed by 50-60 -26.42%, >60 were 19.81%, 30-
40 were 14.15%, 20-30 were 6.60%, <20 were 2.83%. The majority of the patients were
Female i.e. 55.66 %, followed by Male- 44.34 %. The most common clinical features
were Belching in 90%, followed by Heartburn in 85%, Nausea -80%, Vomiting in 78%,
Bloated feeling after meals in 74%, Intolerance to fatty or fried foods in 70%. Bitter
taste in the morning in 65%, Epigastric discomfort in 59%, Pain in right shoulder in
49%, Back pain in 43%. The most common associated factors were Age >40 in 76.41%,
Obese (BMI > 30) in 60%, Female -55.66 %, Family history in 50%, H/o Diabetes -49%,
H/o Liver disease -43%, Non- Veg diet-40%, Diet low in fiber -39% Conclusion: It can
be concluded from our study that The most common clinical features were Belching,
followed by Heartburn, Nausea etc. and the most common associated factors were Age
>40, Obese (BMI > 30), Female sex, Family history, H/o Diabetes, H/o Liver disease,
Non- Veg dietDiet low in fiber etc.