European Journal of Molecular & Clinical Medicine

Abstract

Spinal anaesthesia is a safe and reliable technique for surgery of the lower abdo­men and lower limbs. Nevertheless, some of its characteristics may limit its use for ambulatory surgery, including delayed ambulation, risk of urinary retention, and pain after block regression. The choice of the correct local anaesthetic for spinal anaesthesia is therefore crucial in the ambulatory setting: the ideal anaesthetic should allow rapid onset and offset of its own effect for fast patient discharge with minimal side effects.
Aims: To compare the duration of sensory and motor blocks with use of chloroprocaine, and levobupivacaine as local anaesthetics in spinal anaesthesia.
Materials and method: The present study was a Prospective randomized open label double blind study. This Study was conducted From 18 months, from February 2018 to July 2019 at Department of Anaesthesia, Bankura Sammilani Medical College and Hospital. Total 72 patients were included in this study.
Result: We found that, In group-C, the mean duration of surgery (mean ±s.d.) of the patients was 43.7500 ± 5.6537 mins. In group-L, the mean duration of surgery (mean ±s.d.) of the patients was 44.5833 ± 4.3712 mins. There was no statistically significant difference in ASA gradings in between two groups (p=0.4865). There was no statistically significant difference in mean time to reach peak block height in between two groups (p=0.6142). In group-C, the mean two segment regression time (mean ±s.d.) of the patients was 57.0833 ± 8.5670. In group-L, the mean two segment regression time (mean ±s.d.) of the patients was 80.5833 ± 7.4234. There was statistically significant difference in mean two segment regression time in between two groups (p<0.001). There was statistically significant difference in mean time for regression to L1 in between two groups (p<0.001). There was   no statistically significant difference in PEAK BLOCK HEIGHT in between two groups. (p=0.4004).
Conclusion: we conclude that in patients undergoing unilateral knee arthroscopy, the use of chloroprocaine was associated with decreased time of duration of sensory and motor block and early recovery, early ambulation and early void. There were no statistically significant difference is noted in haemodynamic changes in between two groups. No adverse effects regarding allergic reactions, hypotension, shivering, bradycardia  and nausea and vomiting were  found during intraoperative and postoperative period.