European Journal of Molecular & Clinical Medicine

Abstract

Introduction: Cerebral sinus venous thrombosis (CSVT) is an uncommon condition.Its clinical presentation is varied and often dramatic. Although recognized for more than 100 years. The annual incidence is currently estimated to be 3-4 cases per 1 million people.3 out of 4 people with CSVT are women. It accounts for 10-20 % of the etiology of young strokes in india. Objectives:To study the Clinical features and imaging studies of cerebral venous thrombosis.To study the prognosis based on clinic radiological features.Methodology: Forty patients aged >18 years suspected to have cerebral venous thrombosis based on clinical history and examination were evaluated but only those with confirmed diagnosis (based on neuroimaging) of cerebral venous sinus thrombosis were taken up for the study.Meticulous history, clinical examination, laboratory investigations were carried out in all cases of cerebral venous sinus thrombosis. Cerebral venous thrombosis was confirmed by CT scan (or) conventional MRI (or) MR venogram.Results : Most common radiological finding was hemorrhagic infarction seen in 55% of cases. Empty delta sign was noted in 47.5% of cases. Cord sign was noted in 22.5% of cases. Radiologically most common sinus involved was superior sagittal sinus in 70% of cases followed by transverse sinus in 42.5% of casesLMWH was given in 65% of cases and intravenous unfractionated heparin infusion in 35% of cases, whereas 10% of the patients required decompressive craniotomy.The presence haemorrhagic infarct is associated with bad prognosis.Overall outcome is good with 69.44% of the patients having complete recovery at the time of discharge and overall mortality rate was 10%.Conclusion : The present study emphasizes that CVST is not an uncommon condition. It is an important cause of stroke especially in the peripartum settings and is one of the common causes of stroke in young people.Management with unfractionated heparin, LMWH and oral anticoagulation is appropriate.