Clinical evaluation of two different doses of Tramadol as an adjuvant to Hyperbaric bupivacaine 0.5% in subarachnoid block to prolong the duration of analgesia
European Journal of Molecular & Clinical Medicine,
2023, Volume 10, Issue 3, Pages 1582-1588
AbstractThe aim of present study is to observe the effect of different doses of intrathecal tramadol as an adjuvant in subarachnoid block to prolong the duration of analgesia. All patients were evaluated thoroughly in preanesthetic checkup a day before surgery. During the preanesthetic evaluation a thorough general and systemic examination was done. The patients were examined clinically to note demographic data, baseline heart rate, blood pressure, respiratory rate, oxygen saturation of Hb. History of underlying medical illness, previous surgery, anaesthetic exposures and hospitalization was enquired.
Result: The mean onset time for sensory block in group A patients was observed as 4.62 ± 0.49 minutes and for group B patients it was 4.47 ± 0.51 minutes. We observed onset time for motor block in group A and B that was 5.85 ± 0.61 and 5.56 ± 0.61 minutes respectively. Duration of sensory and motor block in group A patients receiving Tramadol 25 mg was 173.32 ± 12.37 and 158.50 ± 10.71 minutes respectively whereas the duration of sensory and motor block for the patients in group B receiving Tramadol 40 mg was 182.03 ± 10.89 and 167.29 ± 11.09 minutes. The time for demand of dose of rescue analgesic by the patients in both groups was 244.68 ± 8.59 minutes and 306.53 ± 28.56 minutes, significantly higher in patients who received 40 mg tramadol.
Conclusion: The study was carried out in young healthy subjects of either sex belonging to ASA grade 1 and 2. A thorough pre-anaesthetic check-up was carried out. The procedure was explained and informed consent was taken.
Data on onset and offset of sensory and motor block, degree of muscle relaxation, postoperative pain free period were recorded. Vital parameters and incidence of drug related complications were also noted. Observations were tabulated and statistical tests were applied to find out the significance of observations. The observations recorded have been discussed to derive the conclusions.
- Article View: 9
- PDF Download: 10