European Journal of Molecular & Clinical Medicine

Abstract

Background- Depth of invasion (DOI) is an important factor in pre-treatment staging of tongue carcinoma according to AJCC 8th edition.The present study was planned with the aim of assessing the depth of invasion in tongue carcinoma. (HPE) DOI. The object of the study was to see the accuracy of the diffusion weighted imaging (DW-MRI) sequence over the conventiona lMRI compared with histopathology Methods- A total of 70 biopsy proven cases of squamous cell carcinoma of tongue patients, who received pre-treatment MRI including DWI sequence and surgical resection. The depth of invasion was estimated on T2 weighted fat saturated imaging (T2FS) and DWI MRI, measured by a perpendicular line between the reference line at basement membrane and maximum tumor thickness, then compared with the depth of invasion on the histopathology report. Data was collected and evaluated for T stage accuracy of conventional MRI & DWI MRI, then compared with histopathology using the Independent Chi-square test and correlation coefficient.