Abstract

Dengue viral infection is a major public health problem in developing tropic countries. Thrombocytopenia and bleeding manifestations are commonly  associated with dengue patients. The need for platelet transfusion in dengue patients is not clearly defined in them. This study aims at evaluating the effects of prophylactic blood transfusion in dengue patients.
Materials and methods :
About 267 seropositive dengue patients with platelet counts < 20,000/cumm were randomized into two groups. Group A had 135 patients who received prophylactic blood transfusion and group B which had 132 patients who did not receive prophylactic blood transfusion. The outcomes were studied and compared  for statistical significance.
Results :
The patients who received prophylactic blood transfusion did not had a statistically significant reduction in major and minor bleeding  manifestations , transfer to Intensive Care Unit or recovery from thrombocytopenia.
Conclusion :
Prophylactic blood transfusion have no role in treatment of thrombocytopenia in adult dengue patients.