Abstract

The best time to implement such an intervention is unclear, despite research showing that perioperative IMN may lessen postoperative infectious problems in individuals with benign and malignant illness.
Methods: Elective surgical patients with gastric or colorectal cancers who were moderately or severely undernourished as determined by the subjective global assessment (SGA) were randomly assigned to receive parenteral or enteral nutrition for 7 days prior to surgery and for 7 days following it, as opposed to a straightforward control group. The diet consisted of 0.230.04 g nitrogen and 24.65.2 kcal of non-protein per kilogramme per day. Patients in the control group did not receive preoperative nutrition, but instead got postoperatively 600-100 kcal of non-protein plus or minus 62-16 g of crystalline amino acids.
Results: 18.3% of individuals receiving nourishment experienced complications, compared to 33.5% of control patients (P = 0.012). In the control group, 14 patients passed away, whereas 5 of the patients getting nourishment did. The death rates between the two groups were significantly different (2.1% vs. 6.0%, P = 0.003). In comparison to the study patients, the control group's overall inpatient and postoperative stay was substantially longer (29 vs. 22 d, P =0.014) than that of the latter group (23 vs. 12 d, P =0.000).
Conclusion: Preoperative IMN should be advocated in standard practise in patients having surgery for gastrointestinal cancer because to the large influence on infectious complications and a propensity to reduce length of stay.