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Study of Clinicopathological Concordance in the Diagnosis of Papulosquamous Lesions in a Teritiary Care Hospital, Hyderabad

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    • Dr. Radha M, Dr. Keerthana Muppidi, Dr. Pooja Shivkumar, Dr. Divya L
,

Document Type : Research Article

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Abstract

Papulosquamous disorders, characterised by scaly papules and plaques are one of the most common skin dermatoses seen by dermatologists .Some of the examples of papulosquamous skin disorders include lichen planus, psoriasis, pityriasis rosea, pityriasis rubra pilaris, parapsorias etc. Due to clinical and morphological overlap, it is sometimes difficult to make a straight forward clinical diagnosis without histological confirmation. Some of the histopathological features are specific and characteristic for each entity. Hence, combination of proper clinical observation and histopathological study will give a conclusive diagnosis.
Aims and Objectives: The present study aims to analyse various histopathological patterns of papulosquamous lesions of the skin based on the tissue reaction pattern and  assess the concordance of provisional clinical diagnosis and histopathological diagnosis.
Materials And Methods: This is a hospital based retrospective study of 2 year duration from 2021-2022, at Department of pathology. Descriptive data on clinical history and histopathological examination of all the cases  of papulosquamous lesions of skin was collected and results were drawn on various parameters using statistical analysis tools.
Results: Out of  total 90 cases of clinically suspicious papulosquamous disorders, only 74 cases confirmed as various papulosquamous disorders histopathologically with a positive correlation of 82.2 % and negative correlation of 17.7%. Majority (23 cases) were in the age group of 31 to 40 years. There was slight male preponderance with male, female ratio being 1.14:1.The commonest diagnosis was Lichen planus and its variants(23 cases), followed by Psoriasis and its variants(19 cases), eczema(17 cases),pityriasis rosea(5 cases), Lichen nitidus( 3cases), Lichenoid dermatitis(3 cases), Parapsoriasis (2 cases), 1 case each of pityriasis rubra pilaris and chronic cutaneous lupus.
Conclusion: The present study is designed to know the correlation between  the clinical patterns of various papulosquamous disorders and their histopathological diagnosis .There are many studies done on clinical correlation with histopathological diagnosis but still the positive correlation is not reaching upto 100%, some studies have negative correlation of around 40 %. Therefore, more studies are required in this field to appropriately diagnose and manage the  papulosquamous disorders in order to reduce the disease burden and as a key to better patient care.

Keywords

  • Papulosquamous disorders
  • clinical data
  • Clinico-histopathological correlation
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European Journal of Molecular & Clinical Medicine
Volume 10, Issue 2 - Issue Serial Number 2
January 2023
Page 2528-2536
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APA

Dr. Divya L, D. R. M. D. K. M. . D. P. S. (2023). Study of Clinicopathological Concordance in the Diagnosis of Papulosquamous Lesions in a Teritiary Care Hospital, Hyderabad. European Journal of Molecular & Clinical Medicine, 10(2), 2528-2536.

MLA

Dr. Radha M, Dr. Keerthana Muppidi, Dr. Pooja Shivkumar, Dr. Divya L. "Study of Clinicopathological Concordance in the Diagnosis of Papulosquamous Lesions in a Teritiary Care Hospital, Hyderabad". European Journal of Molecular & Clinical Medicine, 10, 2, 2023, 2528-2536.

HARVARD

Dr. Divya L, D. R. M. D. K. M. . D. P. S. (2023). 'Study of Clinicopathological Concordance in the Diagnosis of Papulosquamous Lesions in a Teritiary Care Hospital, Hyderabad', European Journal of Molecular & Clinical Medicine, 10(2), pp. 2528-2536.

VANCOUVER

Dr. Divya L, D. R. M. D. K. M. . D. P. S. Study of Clinicopathological Concordance in the Diagnosis of Papulosquamous Lesions in a Teritiary Care Hospital, Hyderabad. European Journal of Molecular & Clinical Medicine, 2023; 10(2): 2528-2536.

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