A comparative evaluation of PRF, blood clot and collagen scaffold in regenerative endodontics
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 2, Pages 3401-3410
AbstractAim:The present study was conducted evaluate the efficacy of revascularization procedures
for the management of traumatized immature, nonvital, infected permanent teeth.
Materials & Methods:24 adult patients age ranged 13-24 years of both genders with
immature necrotic permanent teeth were classified into 3 groups of 8 each. Group I used
platelet rich fibrin (PRF). Group II used blood clot and group III used sterile collagensponge
scaffold. Patients were recalled regularly and clinical and radiographic evaluation was
performed at 6 months and at 1 year.
Results:In group I, 20% teeth had good and 80% had excellent healing, in group II, 20% had
fair, 50% had good and 30% had excellent healing and in group III, 70% had good and 30%
had excellent healing. In group I, 90% teeth had fair and 10% had good root lengthening, in
group II, 20% had fair and 80% had good root lengthening and in group III, 71% had fair and
29% had good root lengthening. None of the group had excellent root lengthening. Apical
closure was good in 40% and excellent in 60% in group I, good in 25% and excellent in 75%
in group II and fair in 30%, good in 30% and excellent in 60% in group III. Dentinal wall
thickening in group I was fair in 30% and good in 70%, in group II, 50% had fair and 50%
had good and in group III, 30% had fair, 50% had good and 20% had excellent response.
Conclusion:Authors found that PRF and collagen was superior than blood clot in terms of
apical closure and healing. Regenerative healing with different scaffolds is useful method of
preserving immature non- vital permanent teeth.
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