European Journal of Molecular & Clinical Medicine

Abstract

Schiff bases are aldehyde- or ketone-like compounds in which the carbonyl group is replaced by
an imine or azomethine group. Schiff bases are adaptable ligands which are produced from the
condensation of primary amines with carbonyl groups. Production of Schiff base transition metal
complexes by using Schiff base as ligands seems to be enthralling in view of the opportunity of
obtaining coordination compounds of unusual structure and steadiness. They are widely used for
industrial purposes and also exhibit a broad range of biological activities. Characterization using
UV, IR, NMR, Antibacterial, Docking studies of Schiff base and its metal complex is
investigated. The biological activity of the transition metal complexes derived from the Schiff
base ligands has been widely studied. This evaluation summarizes the importance, Scope and
antimicrobial activities of Schiff base metal complexes.