• Register
  • Login

European Journal of Molecular & Clinical Medicine

  • Home
  • Browse
    • Current Issue
    • By Issue
    • By Subject
    • Keyword Index
    • Author Index
    • Indexing Databases XML
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Indexing and Abstracting
    • Peer Review Process
    • News
  • Guide for Authors
  • Submit Manuscript
  • Contact Us
Advanced Search

Notice

As part of Open Journals’ initiatives, we create website for scholarly open access journals. If you are responsible for this journal and would like to know more about how to use the editorial system, please visit our website at https://ejournalplus.com or
send us an email to info@ejournalplus.com

We will contact you soon

  1. Home
  2. Volume 7, Issue 1
  3. Authors

Online ISSN: 2515-8260

Volume7, Issue1

HANTAVIRUS AND ITS ASSOCIATED IMMUNOPATHOGENESIS

    Ananya R Smiline Girija Ezhilarasan D

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 2030-2037

  • Show Article
  • Download
  • Cite
  • Statistics
  • Share

Abstract

Hantavirus is a zoonotic virus manifesting two vital clinical symptoms viz., hemorrhagic fever with renal syndrome and cardiopulmonary syndrome. With a sudden onset of fatigue, fever, and body aches, in extreme cases can lead to shortness of breath and had resulted in major outbreaks in past decades. Pro- inflammatory cytokine responses and reticulo endothelial systems take the lead role in establishing the immuno-pathogenesis of the hantavirus disease. The virus genome consists of these segments of negative stranded RNA, where the large (L) segment encodes the viral RNA polymerase, the medium (M) segment the glycoprotein precursor which is co-translationally cleaved into the envelope glycoproteins Gn and Gc, and the small (S) segment the nucleocapsid protein (N). Hantavirus are divided into Old world and New world hantavirus based on the geographic regions in which they occur. They are strictly associated with their reservoirs hosts which are rodents, but from recent researches reported, also insectivores. Both innate and cellular immune responses function effectively in evading the viral replication, however the mutations and the typical variations in the virus finally establishes a disease in humans. This review thus provides an overview on hanta virus and its associated immune-pathogenesis.
Keywords:
    Hantavirus immunopathogenesis Viral replication hosts UUV rodents - reservoirs
  • PDF (256 K)
  • XML
(2020). HANTAVIRUS AND ITS ASSOCIATED IMMUNOPATHOGENESIS. European Journal of Molecular & Clinical Medicine, 7(1), 2030-2037.
Ananya R; Smiline Girija; Ezhilarasan D. "HANTAVIRUS AND ITS ASSOCIATED IMMUNOPATHOGENESIS". European Journal of Molecular & Clinical Medicine, 7, 1, 2020, 2030-2037.
(2020). 'HANTAVIRUS AND ITS ASSOCIATED IMMUNOPATHOGENESIS', European Journal of Molecular & Clinical Medicine, 7(1), pp. 2030-2037.
HANTAVIRUS AND ITS ASSOCIATED IMMUNOPATHOGENESIS. European Journal of Molecular & Clinical Medicine, 2020; 7(1): 2030-2037.
  • RIS
  • EndNote
  • BibTeX
  • APA
  • MLA
  • Harvard
  • Vancouver
  • Article View: 53
  • PDF Download: 100
  • LinkedIn
  • Twitter
  • Facebook
  • Google
  • Telegram
Journal Information

Publisher:

Email:  info@ejmcm.com

  • Home
  • Glossary
  • News
  • Aims and Scope
  • Privacy Policy
  • Sitemap

Editorial Team:  editor@ejmcm.com

For Special Issue Proposal : chiefeditor.ejmcm@gmail.com / info@ejmcm.com

This journal is licensed under a Creative Commons Attribution 4.0 International (CC-BY 4.0)

Powered by eJournalPlus