• Register
  • Login

European Journal of Molecular & Clinical Medicine

  • Home
  • Browse
    • Current Issue
    • By Issue
    • By Subject
    • Keyword Index
    • Author Index
    • Indexing Databases XML
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Indexing and Abstracting
    • Peer Review Process
    • News
  • Guide for Authors
  • Submit Manuscript
  • Contact Us
Advanced Search

Notice

As part of Open Journals’ initiatives, we create website for scholarly open access journals. If you are responsible for this journal and would like to know more about how to use the editorial system, please visit our website at https://ejournalplus.com or
send us an email to info@ejournalplus.com

We will contact you soon

  1. Home
  2. Volume 7, Issue 6
  3. Authors

Online ISSN: 2515-8260

Volume7, Issue6

Effect of BergeniaLigulata on Metabolic Enzymes of Glucose Homeostasis and Its Correlation With Antioxidant Activity in Streptozotocin Induced Diabetic Rats

    Nagarani K Swathi P Eswar Kumar K

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 6, Pages 187-202

  • Show Article
  • Download
  • Cite
  • Statistics
  • Share

Abstract

Abstract: Diabetes mellitus is characterized by loss of glucose homeostasis as a result of impaired secretion and function of insulin. The present study was designed to evaluate the role of flower extractof Bergenialigulataagainst diabetesin Streptozotocin induced diabetic rats. Albino Wistar rats weighing 120-150g of either sex were selected for the study.After a week of acclimatization, the rats were subjected to overnight fasting. Diabeteswas induced by intraperitoneal injection of Streptozotocin, freshly dissolved in citrate bufferpH 4.5.In the present study the STZ control animals showed enhanced gluconeogenic enzymes and diminished glycolytic enzymes there by it disturb the glucose homeostasis and diminished insulin production leads increased serum glucose levels. Treatment with flower extract ofBergenialigulata(AFBL) showed significant balancing of glucose homeostasis through reduction in gluconeogenic enzymes and elevation of glycolytic enzymes.The selected flower extract ofBergenialigulata(AFBL) showed in vivo antioxidant activity, antihyperglycemic activity, hepatoprotective activity, nephroprotective activity and finally glucose homeostatic activity might be due to the potent phytoconstituents present in the selected flower extract
Keywords:
    Bergenialigulata Streptozotocin wistarrats Diabetes mellitus
  • PDF (1215 K)
  • XML
(2020). Effect of BergeniaLigulata on Metabolic Enzymes of Glucose Homeostasis and Its Correlation With Antioxidant Activity in Streptozotocin Induced Diabetic Rats. European Journal of Molecular & Clinical Medicine, 7(6), 187-202.
Nagarani K; Swathi P; Eswar Kumar K. "Effect of BergeniaLigulata on Metabolic Enzymes of Glucose Homeostasis and Its Correlation With Antioxidant Activity in Streptozotocin Induced Diabetic Rats". European Journal of Molecular & Clinical Medicine, 7, 6, 2020, 187-202.
(2020). 'Effect of BergeniaLigulata on Metabolic Enzymes of Glucose Homeostasis and Its Correlation With Antioxidant Activity in Streptozotocin Induced Diabetic Rats', European Journal of Molecular & Clinical Medicine, 7(6), pp. 187-202.
Effect of BergeniaLigulata on Metabolic Enzymes of Glucose Homeostasis and Its Correlation With Antioxidant Activity in Streptozotocin Induced Diabetic Rats. European Journal of Molecular & Clinical Medicine, 2020; 7(6): 187-202.
  • RIS
  • EndNote
  • BibTeX
  • APA
  • MLA
  • Harvard
  • Vancouver
  • Article View: 68
  • PDF Download: 102
  • LinkedIn
  • Twitter
  • Facebook
  • Google
  • Telegram
Journal Information

Publisher:

Email:  info@ejmcm.com

  • Home
  • Glossary
  • News
  • Aims and Scope
  • Privacy Policy
  • Sitemap

Editorial Team:  editor@ejmcm.com

For Special Issue Proposal : chiefeditor.ejmcm@gmail.com / info@ejmcm.com

This journal is licensed under a Creative Commons Attribution 4.0 International (CC-BY 4.0)

Powered by eJournalPlus