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  2. Volume 7, Issue 2
  3. Authors

Online ISSN: 2515-8260

Volume7, Issue2

The Effects of Purified Staphylococcal Enterotoxin A on Gene Expression of Nuclear Factor Кappa B (NF-КB) in Rabbits

    Ayat Ali Mahmood Ahmad Darweesh Jabar Muthana Ibrahim Maleek

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 4319-4324

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Abstract

This study aimed to determine the effects of Staphylococcal enterotoxin A on NF-KB gene expression in rabbits. Firstly, SEA was isolate, purified and identified from one strain of Staph-ylococcus aureus collected from urine sample, and had identified by biochemical and molecu-lar methods. Then ,Staphylococcal enterotoxin A was purified by chromatography technique . All purified fractions of SEA was determined by ELISA kit. Finally, 5mgml of SEA was injected intravenously to rabbits in order to demonstrate its effects on NF-KB gene expression. At the end of this experiment, the gene expression of NF-KB increased to 9.1 in compression with control group with 1 of fold time (P = 0.045)
Keywords:
    Staphylococcal enterotoxin A Chromatography technique Anion exchanger sephadex G-100 NF-KB gene expression
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(2020). The Effects of Purified Staphylococcal Enterotoxin A on Gene Expression of Nuclear Factor Кappa B (NF-КB) in Rabbits. European Journal of Molecular & Clinical Medicine, 7(2), 4319-4324.
Ayat Ali Mahmood; Ahmad Darweesh Jabar; Muthana Ibrahim Maleek. "The Effects of Purified Staphylococcal Enterotoxin A on Gene Expression of Nuclear Factor Кappa B (NF-КB) in Rabbits". European Journal of Molecular & Clinical Medicine, 7, 2, 2020, 4319-4324.
(2020). 'The Effects of Purified Staphylococcal Enterotoxin A on Gene Expression of Nuclear Factor Кappa B (NF-КB) in Rabbits', European Journal of Molecular & Clinical Medicine, 7(2), pp. 4319-4324.
The Effects of Purified Staphylococcal Enterotoxin A on Gene Expression of Nuclear Factor Кappa B (NF-КB) in Rabbits. European Journal of Molecular & Clinical Medicine, 2020; 7(2): 4319-4324.
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