Eosinophil count as the predictor of main outcomes of COVID 19:case-control study
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 2, Pages 4429-4438
AbstractBackground: eosinopenia is habitually encountered hematological parameter in patients with COVID 19,its precise relevance with diagnosis, seriousness, and detrimental terminal consequences in COVID 19 cases is ambiguous.
Objectives: the study was implemented to construct a link between eosinopenia and COVID 19 concerning diagnostic usefulness, anticipation of deleterious ramifications, and lethality in COVID 19 cases.
Materials and methods: A random sample of (100) patients with acute respiratory illness subjected to admission in medical department in Al-Hussein teaching hospital were incorporated in the analysis ,(50) cases with COVID-19 pneumonia and (50) control with influenza A pneumonia, both accused by clinical and radiological attributes and verified by Polymerase chain reaction. Eosinophil total, laboratory analysis of inflammatory indices and organ function was accomplished for the sum total of cases and controls.
Results: mean age is (63.8400), (53) males and(47) females,(52) of entire sample were eosinopenic ,(48) were non-eosinopenic,(46) of eosinopenic patient belong to COVID-19 category but just (6) belong to control category with significant difference (p value=0.001).(27) patients from COVID-19 category elected to be transferred to ICU services, concurrently just( 5) patients from control category seek ICU service ,(26 ) patient from COVID-19 category who were admitted to ICU are eosinopenic meanwhile just one in control category was eosinopenic( odd ratio:1.053).(26) patients of COVID-19 category died meanwhile (5) patients from control category died,(25) patients who died in COVID-19 category were eosinopenic meanwhile just one in control category was eosinopenic(Odd ratio:1.565).
Conclusion: admission eosinopenia is a dependably applicable, easily intelligible test for prompt anticipation of diagnosis as well as unfavorable consequences of COVID 19.
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