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  2. Volume 7, Issue 8
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Online ISSN: 2515-8260

Volume7, Issue8

Correlation of CD4 Count andNeutrophil-Lymphocyte Ratio in Human Immunodeficiency Virus-Acquired Immunodeficiency Syndrome (HIV-AIDS)Patients

    Kartika Handayani Sudirman Katu Syakib Bakri Risna Halim Andi Makbul Aman Haerani Rasyid Hasyim Kasim Arifin Seweng

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 8, Pages 985-993

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Abstract

Background: Human Immunodeficiency Virus (HIV) is an RNA virus that causes a decrease in the immune system and destroys specific white blood cells called T-helper lymphocytes or Cluster of Differentiation 4 (CD4); CD4 is a parameter in HIV-AIDS patients while NLR is a simple parameters that were used to assess inflammatory status.
Purpose: This study aims to determine the relationship between CD4 and NLR levels in HIV-AIDS patients.
Methods: This is an observational study with a cross-sectional design conducted in September 2019-September 2020. The study populations were all HIV patients that hospitalized and outpatient at Dr. Wahidin Sudirohusodo Hospital and his network hospital. Data were analyzed descriptively to found out the association between CD4 and NLR levels in HIV-AIDS patients using the Spearman trial.  Results: A total of 150 subjects, consist of 62 (41.3%) subjects at age 30-39 years, 122 (81.3%) male subjects, 108 (72%) subjects who had PEM nutritional status, and 102 subjects (68%) subject with CD4 count <50. Based on the Spearman test, there is negative correlation of CD4 and NLR in HIV-AIDS patient.
Conclusion: There are significant negative correlation between CD4 and NLR in HIV-AIDS patients at Dr. Wahidin Sudirohusodo Makassar, which higher NLR correlates with the lower value of CD4..
Keywords:
    Human immunodeficiency virus acquired immunodeficiency virus cluster differentiation 4 neutrophil-lymphocyte ratio
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(2020). Correlation of CD4 Count andNeutrophil-Lymphocyte Ratio in Human Immunodeficiency Virus-Acquired Immunodeficiency Syndrome (HIV-AIDS)Patients. European Journal of Molecular & Clinical Medicine, 7(8), 985-993.
Kartika Handayani; Sudirman Katu; Syakib Bakri; Risna Halim; Andi Makbul Aman; Haerani Rasyid; Hasyim Kasim; Arifin Seweng. "Correlation of CD4 Count andNeutrophil-Lymphocyte Ratio in Human Immunodeficiency Virus-Acquired Immunodeficiency Syndrome (HIV-AIDS)Patients". European Journal of Molecular & Clinical Medicine, 7, 8, 2020, 985-993.
(2020). 'Correlation of CD4 Count andNeutrophil-Lymphocyte Ratio in Human Immunodeficiency Virus-Acquired Immunodeficiency Syndrome (HIV-AIDS)Patients', European Journal of Molecular & Clinical Medicine, 7(8), pp. 985-993.
Correlation of CD4 Count andNeutrophil-Lymphocyte Ratio in Human Immunodeficiency Virus-Acquired Immunodeficiency Syndrome (HIV-AIDS)Patients. European Journal of Molecular & Clinical Medicine, 2020; 7(8): 985-993.
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