European Journal of Molecular & Clinical Medicine

Abstract

Purpose: to assess the effect of Rh immunization on the state of indicators of innate humoral immunity in the fetus, such as immunoglobulins A, M, G, circulating immune complexes of large and small quantities, cytokines IL-1β and IL-8, which play a decisive role in the pathogenesis of the development of a pathological process ... Materials and Methods: Immunological studies were carried out on 17 umbilical cord blood sera from fetuses with hemolytic disease, which were taken by transabdominal cordocentesis in pregnant women between 24 and 33 weeks of gestation with Rh immunization at the Republican Perinatal Center for 2019 and 2020. All studies were carried out in the laboratory of