Endolumbal Nootropic-Ozone Therapy In Complex Treatment Of Patients With Complicated Spinal Injury In Acute Period
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 3, Pages 1571-1576
AbstractAbnormal spinal trauma is the most severe damage to the human musculoskeletal system and is found in the 2.3 -4.7% of cases [3, 7, 8]. The lethality of these injuries is up to 25-30% [7, 9, 10], and disability when it reaches up to 86-94% [(2, 7, 8]. In much of the results of treatment depend on the quality of medical aid in acute period of complicated spinal injuries in such cases, the purpose of early and effective treatment of these patients is not only the restoration of the basic function of the spine, but also the development of mechanisms of compensation broken spinal cord functions. Therefore, timely and efficiently provided medical care in specialized institutions significantly improves outcomes of injuries and enhances the quality of life of the victims.
In the last few years to treat complicated injuries of the spine, along with surgical method uses different medications that can help improve metabolism and blood circulation, reduce edema and medications for the injured area of the spinal cord.
So far, have been widely used corticosteroid medications (dexamethasone and methylprednisolone) in acute period of injury. Use of steroid hormones improves metabolism in acute period of spinal cord injury. Corticosteroids also provide stabilizing membranes, reduces edema, "clean" acid radicals, reduce metabolism products contribute to cerebrospinal fluid diffusion of oxygen into the fabric. But the drugs have significant side effects, as well as a number of reasons.
Now continue to search for drugs and methods aimed at correlation metabolic violations in the spinal cord, resulting in hypoxia and to improve treatment outcomes.
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