European Journal of Molecular & Clinical Medicine

Abstract

(CD) is a chronic inflammatory disorder of the upper small intestine caused by an inflammatory T-cell response to the ingestion or storage proteins in wheat (gliadin), rye (secalin), and barley (hordein), which are collectively called “gluten”, and possibly oat products. (ATD) is the most common autoimmune condition, an acting approximately 2% of the female population and 0.2% of the male population. Thyroiditis has been repeatedly associated with celiac disease. (TTG-A) has proved to be a very specific indicator to identify patients with CD. (anti-TPO), (anti-TG) and (anti-TSHR) is a main feature of autoimmune thyroid disease.
Methods; One hundred and sixteen submitted in this study 86 patient for CD and 30 control (healthy), tested for (TTG-IgG, TTG-IgA, Anti-TSH Anti-TPO and Anti-TG) by use ELISA method.
Results; (TTG-IgG) with (TTG-IgA, Anti-TSH) show statistical significant, (TTG-IgG) with (Anti-TPO, Anti-TG) show statistical non-significant. (TTG-IgA) with (TTG-IgG, Anti-TSH) show statistical significant. (TTG- IgA) with (Anti-TPO, Anti-TG) show statistical non-significant.
Conclusion; There are a strong association between CD and autoimmune thyroid disorders