A Multidisciplinary Approach To The Treatment Of Buschke-Lowenstein Tumor During Pregnancy
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 10, Pages 352-358
AbstractBuschke-Lowenstein tumor (verrucous cancer, verrucous carcinoma) is a disease of the anogenital area, with the human papillomavirus (HPV) as the causative agent, mainly of a low-oncogenic type 6 or 11. It is characterized by large cauliflower-type vegetation, progressive invasive growth and at the same time by a benign histological pattern [1-4]. It is a sexually-transmitted infection. This pathology is named after the authors A. Buschke and L. Lowenstein, who first described huge condyloma accuminatum of a penis in 1925. The progression of condyloma accuminatum to the size of a Bushke-Levenstein tumor (BLT) is very rare. This pathology occurs in about 0.1% of sexually active people . Histologically, BLT reveals benign features of a typical condyloma accuminatum (acanthosis, papillomatosis, koilocytosis). Cases of BLT malignancy have been described, but they are extremely rare . Usually BLT develops rather slowly, sometimes within several years, but there have been specified the cases of fast development of BLT with solitary condylomata during pregnancy [7, 8].
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