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  2. Volume 7, Issue 6
  3. Author

Online ISSN: 2515-8260

Volume7, Issue6

Apoptosis: Molecular Basis Of Programmed Cell Death And Its Role In Cancer

    Dr ShabnamRafikShaha, Dr Ritu, Dr Pushpa, Dr AjayJatoliya, Dr G. Jaysee John

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 6, Pages 1706-1713

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Abstract

Our somatic cells are reproduced by the process of mitosis and nearly death of all of them will be by apoptosis, a physiological route of cellular suicide. Cancers can crop up when imbalance of this process occures, by an increased cell proliferation or a decreased cell death. Our information about the mechanisms of apoptosis has improved perceptionsabout origin and progress of  some cancers. In  few cases resistance to apoptosis may explain the cause of failure of cancer therapies.  With the knowledge of apoptotic mechanisms, the treatment  plans  are developing by  promoting apoptosis of cancer cells and bylimiting  death of normal cells.. The goal of this review is to propose a broad summary of current information on apoptosis,it’s role in cancer and role of some proteins like  caspaces,  Bcl-2, IAP, p53 in apoptosis.
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(2020). Apoptosis: Molecular Basis Of Programmed Cell Death And Its Role In Cancer. European Journal of Molecular & Clinical Medicine, 7(6), 1706-1713.
Dr ShabnamRafikShaha, Dr Ritu, Dr Pushpa, Dr AjayJatoliya, Dr G. Jaysee John. "Apoptosis: Molecular Basis Of Programmed Cell Death And Its Role In Cancer". European Journal of Molecular & Clinical Medicine, 7, 6, 2020, 1706-1713.
(2020). 'Apoptosis: Molecular Basis Of Programmed Cell Death And Its Role In Cancer', European Journal of Molecular & Clinical Medicine, 7(6), pp. 1706-1713.
Apoptosis: Molecular Basis Of Programmed Cell Death And Its Role In Cancer. European Journal of Molecular & Clinical Medicine, 2020; 7(6): 1706-1713.
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