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  2. Volume 7, Issue 5
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Online ISSN: 2515-8260

Volume7, Issue5

Low Abundance Of Capnophiles In The Saliva Of Oral Squamous Cell Carcinoma Patients- A Metagenomic Analysis

    Prasada Rao Namburi , Krishnan Mahalakshmi, Sankar Leena Sankari, Venkatesan Naveen Kumar

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 1375-1379

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Abstract

Objective: Alterations in microbiome have been linked to Oral squamous cell carcinoma (OSCC) by few earlier studies. We aimed to assess such changes in OSCC patients. Methods: 16S rRNA metagenomic analysis of saliva samples from OSCC patients and health were performed by the latest next generation sequencing (MinION nanopore platform) using pan-eubacterial primers that amplify the entire 16S rRNA gene. The sequences were analysed with MG-RAST. Results: Capnophilic Capnocytophaga species, (Capnocytophaga gingivalis Capnocytophaga ochracea, Capnocytophaga sputigena, Capnocytophaga cynodegmi and Capnocytophaga canimorsus) were found to be in low abundance among OSCC patients compared to the healthy subjects. Conclusion: These findings suggest the association of Capnocytophaga species to health.
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(2020). Low Abundance Of Capnophiles In The Saliva Of Oral Squamous Cell Carcinoma Patients- A Metagenomic Analysis. European Journal of Molecular & Clinical Medicine, 7(5), 1375-1379.
Prasada Rao Namburi , Krishnan Mahalakshmi, Sankar Leena Sankari, Venkatesan Naveen Kumar. "Low Abundance Of Capnophiles In The Saliva Of Oral Squamous Cell Carcinoma Patients- A Metagenomic Analysis". European Journal of Molecular & Clinical Medicine, 7, 5, 2020, 1375-1379.
(2020). 'Low Abundance Of Capnophiles In The Saliva Of Oral Squamous Cell Carcinoma Patients- A Metagenomic Analysis', European Journal of Molecular & Clinical Medicine, 7(5), pp. 1375-1379.
Low Abundance Of Capnophiles In The Saliva Of Oral Squamous Cell Carcinoma Patients- A Metagenomic Analysis. European Journal of Molecular & Clinical Medicine, 2020; 7(5): 1375-1379.
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