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  1. Home
  2. Volume 7, Issue 8
  3. Author

Online ISSN: 2515-8260

Volume7, Issue8

Silver Nanoparticles With Antimicrobial Activities Against Streptococcus Mutans And Their Cytotoxic Effect- Review Article

    Dr. Vijay sir, Karthiga.N

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 8, Pages 1837-1847

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Abstract

Microbial resistance represents a challenge for the scientific community to develop new bioactive compounds. The goal of this research was to evaluate the antimicrobial activity of silver nanoparticles (AgNPs) against a clinical isolate of Streptococcus mutans, antibiofilm activity against mature S. mutans biofilms and the compatibility with human fibroblasts. The antimicrobial activity of AgNPs against the planktonic clinical isolate was size and concentration dependent, with smaller AgNPs having a lower minimum inhibitory concentration. A reduction of 2.3 log in the number of colony-forming units of S. mutans was observed when biofilms grown in a CDC reactor were exposed to 100 ppm of AgNPs of 9.5 ± 1.1 nm. However, AgNPs at high concentrations (N10 ppm) showed a cytotoxic effect upon human dermal fibroblasts. AgNPs effectively inhibited the growth of a planktonic S. mutans clinical isolate and killed established S. mutans biofilms, which suggests that AgNPs could be used for prevention and treatment of dental caries. Further research and development are necessary to translate this technology into therapeutic and preventive strategies.
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(2020). Silver Nanoparticles With Antimicrobial Activities Against Streptococcus Mutans And Their Cytotoxic Effect- Review Article. European Journal of Molecular & Clinical Medicine, 7(8), 1837-1847.
Dr. Vijay sir, Karthiga.N. "Silver Nanoparticles With Antimicrobial Activities Against Streptococcus Mutans And Their Cytotoxic Effect- Review Article". European Journal of Molecular & Clinical Medicine, 7, 8, 2020, 1837-1847.
(2020). 'Silver Nanoparticles With Antimicrobial Activities Against Streptococcus Mutans And Their Cytotoxic Effect- Review Article', European Journal of Molecular & Clinical Medicine, 7(8), pp. 1837-1847.
Silver Nanoparticles With Antimicrobial Activities Against Streptococcus Mutans And Their Cytotoxic Effect- Review Article. European Journal of Molecular & Clinical Medicine, 2020; 7(8): 1837-1847.
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