IDENTIFICATION OF HELICOBACTER PYLORI AND ITS CONNECTION WITH ORAL CANCER IN THE ORAL CAVITY:A CROSS SECTIONAL STUDY
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 9, Pages 970-977
AbstractHelicobacter pylori, group I carcininogen bacteria. The possible role of this organism in oral cavity has been studied in this study. We adopted Polymerase Chain Reaction to identify the organism in subjects with gingivitis, periodontitis, recurring oral aphthae, oral cancer and gastric cancer and compared with control group. The virulence of this organism in oral cavity has been detected by ELISA by identifying proteins such as CAG A and VAC A. For statistically important (p value 0.00001) in prevalence of Helicobacter pylori in the diseased groups it is compared with the control community. Helicobacter pylori positive saliva appears to be methodologically important (p value 0.00001) for comparative analysis of all virulent proteins distribution in the control community of the diseased population. 24 subjects which is showed in the existence of Helicobacter pylori, 15 had CAG A protein, 19 had VAC A protein and nine had all the virulent proteins. All the three subjects were useless but an organism’s existence was demonstrated by all of them out of which two showed positivity for all proteins. These three subjects have seen the absence of HPV 16 and 18. With nicotine habits and the presence of organism substantial findings were found in patients. For Helicobacter pylori Rima Oris can serve as a niche. The oral cavity is likely to be high due to the similarities between the oral mucosa and the gastric mucosa for the propensity of CAG A and VAC A proteins which is to be pathogenic.
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