European Journal of Molecular & Clinical Medicine

Abstract

BACKGROUND: The primary function of amniotic fluid is protection of the growing foetus while providing nutrition. A considerable amount of research has been conducted to evaluate interventions to improve amniotic fluid index and the subsequent impact on foetal growth restriction and oligohydramnios. However, there isn't any conclusive evidence hence this study aims to compare the effect of oral amino acid supplements and intravenous infusions in pregnancies with oligohydramnios and foetal growth restriction. 
AIM: To compare the effect of oral amino acid supplementation vs intravenous amino acid infusion on amniotic fluid index and perinatal outcome in pregnancy complicated by oligohydramnios and foetal growth restriction
OBJECTIVES: To compare the effectiveness of oral amino acid supplementation vs intravenous amino acid infusion in pregnancy having oligohydramnios and foetal growth restriction. To study the increase in amniotic fluid index in pregnancy with foetal weight gain. To study the interval growth rate of baby after two weeks and four weeks of therapy.
MATERIAL AND METHOD: This Semi experimental study will be conducted in Department of Obstetrics and Gynaecology, AVBRH, Datta Meghe Institute of Medical Sciences, Sawangi (Meghe), Wardha. A total of 104 clinically and sonographically proven cases of foetal growth restriction & Oligohydramnios in third trimester attending antenatal clinic or admitted in wards, fulfilling the exclusion and inclusion criteria will be comprise the study groups. After providing oral supplements or intravenous infusions arbitrarily, repeat ultrasonography will be done after two weeks and four weeks of therapy.
EXPECTED RESULTS: We compare from our results the effect of oral amino acid supplementation vs intravenous amino acid infusion on amniotic fluid index and perinatal outcome in pregnancies complicated by oligohydramnios and foetal growth restriction.