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Antitubercular Drug Induced Hepatotoxicity: A Review

    Authors

    • Manjot Kaur Gill 1
    • Rakesh Raman Patyar 2
    • Sazal Patyar 3

    1 School of Pharmaceutical Sciences, Lovely Professional University, Phagwara (India)

    2 Department of Technical Education and Industrial Training, Government of Punjab (India).

    3 No Affiliation Available.

,

Document Type : Research Article

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Abstract

Hepatotoxicity is an emerging medical problem. It has multiple etiological factors but most common reason is chronic treatment with certain drugs during the cure of numerous life threatening diseases. Antitubercular drugs are the leading cause of injury or damage to liver. So this is a challenging task to prevent the drug induced hepatotoxicity during tuberculosis treatment. Generally it results into interruption of treatment and cause re-emergence of this disease. This review article highlights the different mechanisms of anti-tubercular drug induced hepatotoxicity, its incidence and clinical management.

Keywords

  • Mycobacterium Tuberculosis
  • Anti-tubercular drugs
  • Drug induced hepatotoxicity
  • Isoniazid
  • Rifampicin
  • Pyrazinamide
  • Hepatotoxins
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European Journal of Molecular & Clinical Medicine
Volume 7, Issue 7
November 2020
Page 2840-2847
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  • Article View: 343
  • PDF Download: 1,338

APA

Gill, M. K., Patyar, R. R., & Patyar, S. (2020). Antitubercular Drug Induced Hepatotoxicity: A Review. European Journal of Molecular & Clinical Medicine, 7(7), 2840-2847.

MLA

Manjot Kaur Gill; Rakesh Raman Patyar; Sazal Patyar. "Antitubercular Drug Induced Hepatotoxicity: A Review". European Journal of Molecular & Clinical Medicine, 7, 7, 2020, 2840-2847.

HARVARD

Gill, M. K., Patyar, R. R., Patyar, S. (2020). 'Antitubercular Drug Induced Hepatotoxicity: A Review', European Journal of Molecular & Clinical Medicine, 7(7), pp. 2840-2847.

VANCOUVER

Gill, M. K., Patyar, R. R., Patyar, S. Antitubercular Drug Induced Hepatotoxicity: A Review. European Journal of Molecular & Clinical Medicine, 2020; 7(7): 2840-2847.

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