The Concept of Dual trigger is better then the more established use of hCG trigger in triggering oocyte maturation as well as helping in prevention of OHSS in GnRH antagonist IVF/ICSI Cycle a retrospective study
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 11, Pages 480-489
Abstract: The study is conducted to identify whether the concept of application of “dual trigger is more useful than the more standard hCG Trigger in the prevention of OHSS and for acquiring and in determining other major aspects such as retrieval of more number of mature oocytes, followed by better fertilization rate, with more usable embryos and better pregnancy outcomes among the two methods. “Dual trigger was first defined as the concept of a combination of drugs i.e GnRH agonist and a low dose hCG to help in triggering final oocyte maturation specially in preventing OHSS in high ovarian responders” “hCG trigger has been since a long time used for triggering oocyte maturation because of its similarity to LH and half life and because it produces a action as similar to in an natural menstrual cycle.
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