AN OVERVIEW OF TRIAZOLE SCAFFOLD: SYNTHESIS AND PHARMACOLOGICAL SIGNIFICANCE (2010-2020)
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 3, Pages 5580-5590
AbstractAmong heterocyclic compounds, triazole has become an important one in the development of new drugs. A wide array of drugs comprising triazole nuclei display wide range of pharmaceutical applications which include anticonvulsants, antimalarial, antimicrobial, antitumor, antiviral, antiproliferative , anticancer , antioxidants, analgesics, antifungal , antiplasmodial , antibacterial , immunostimulants and antidiabetic. This pharmacological significance of the triazole nucleus has driven the interest of researchers to develop potent triazole derivatives with auspicious biological activities.
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