A Comparative Study of Middle Cerebral and Umbilical Arteries Doppler Indices in Controlled Versus Uncontrolled Insulin-Dependent Pregestational Diabetic Pregnancies

Mahmoud Ahmed Ismail Abd El Hameed, Mona Mohamed Sediek, Rasha Omar Fathy El Komy, Moutaz Mahmoud El-Sherbini ,Basma Makin Abd El Azeem

Online ISSN: 2515-8260

Volume7, Issue11

A Comparative Study of Middle Cerebral and Umbilical Arteries Doppler Indices in Controlled Versus Uncontrolled Insulin-Dependent Pregestational Diabetic Pregnancies

Rasha Omar Fathy El Komy, Moutaz Mahmoud El-Sherbini ,Basma Makin Abd El Azeem Mahmoud Ahmed Ismail Abd El Hameed, Mona Mohamed Sediek

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 2420-2426

Abstract

Objectives: To evaluate the effect of glycemic control on umbilical and fetal middle cerebral arteries Doppler indices in pregestational diabetic pregnant women.
Methods: 60 insulin-dependent pregestational diabetic pregnant women were included and equally divided into two groups according to HbA1C levels namely; controlled diabetics ( HbA1C < 6.5 %) and uncontrolled diabetics (HbA1C ≥ 6.5 %). UA, MCA Doppler indices (resistance index and pulsatility index) and Cerebroplacental Doppler ratio were measured for every patient.
Results: There was no statistically significant differences in umbilical artery, middle cerebral artery Doppler indices and cerebroplacental ratio between the controlled & uncontrolled pregestational diabetic pregnant women.
Conclusion:Doppler indices of placental or fetal circulation are unaffected by maternal glycemic control in pregestational diabetic pregnant women.

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