• Register
  • Login

European Journal of Molecular & Clinical Medicine

  1. Home
  2. Using of calprotectin and lactoferrin levels in early detection of acute uncomplicated appendicitis in children

Current Issue

By Issue

By Author

By Subject

Author Index

Keyword Index

About Journal

Aims and Scope

Editorial Board

Publication Ethics

Indexing and Abstracting

Related Links

FAQ

Peer Review Process

Journal Metrics

News

Using of calprotectin and lactoferrin levels in early detection of acute uncomplicated appendicitis in children

    Authors

    • Athir Ahmed Kadium 1
    • Alaa Mohammed Ali Al Baazi 2
    • Mahmood Mosa Mahmood 3

    1 M.B.Ch.B F.I.C.M.S, Pediatric surgeon. Kirkuk Health Directorate, Iraq

    2 M.B.Ch.B F.I.B.M.S,Pediatric surgeon. Al Diwaniyah Health Directorate, Iraq

    3 M.B.Ch.B F.I.B.M.S,Pediatric surgeon. Nineveh Health Directorate, Iraq

,
  • Article Information
  • Download
  • Export Citation
  • Statistics
  • Share

Abstract

This study was conducted in Kirkuk city for the period from December, 2019 to June 2020, and included 50 children with acute appendicitisand 50 children without any other disease, where the ages of children in both groups ranged from 3-12 years. The study included collecting information from children in both groups, including gender, age, living situation, number of family members, standard of living and social as well as the number of family members, number of rooms in the house. Amount of 5 ml of blood samples were collected from all the children included in this study, where the blood samples were separated by the centrifuge device and the serum samples were separated from them and kept in the refrigerator until the tests for determination of calprotectin and lactoferrin by ELISA and CRP by immunofluorescence. In this study, there were no significant difference between the 2 groups regarding age, sex and residence. The study found that, 95% of children with appendicitis was suffered from abdominal pain , 50% with fever and weight loss, 48% with nausea and 40% with vomiting. The study revealed a significant elevated level of calprotectin in children with appendicitis as compared with healthy children(18.54±4.25 vs 11.37±3.28 ng/ml) (P<0.001). The study also exposed a significant higher level of lactoferrin in children with appendicitis as compared with healthy children(10.51±1.52 vs 2.18±0.19 ng/ml) (P<0.001).The study showed that the maximum means of calprotectin and lactoferrin in children with appendicitis were observed in those with abdominal pain, followed by vomiting. The study revealed a significant positive correlation between calprotectin and lactoferrinlevel among children with acute appendicitis.The mean serum level of CRP was significantly elevated in children with acute appendicitiscompared to control group (27.57 ± 4.22 and 5.57 ± 3.9 mg/dl) respectively at a P value < 0.001. Conclusions:The study showed a significant relation of calprotectin and lactoferrin withappendicitis.

Keywords

  • Calprotectin
  • lactoferrin
  • CRP
  • Appendicitis
  • children
  • XML
  • PDF 472.38 K
  • RIS
  • EndNote
  • Mendeley
  • BibTeX
  • APA
  • MLA
  • HARVARD
  • VANCOUVER
    • Article View: 258
    • PDF Download: 319
European Journal of Molecular & Clinical Medicine
Volume 7, Issue 1
January 2020
Page 4335-4341
Files
  • XML
  • PDF 472.38 K
Share
Export Citation
  • RIS
  • EndNote
  • Mendeley
  • BibTeX
  • APA
  • MLA
  • HARVARD
  • VANCOUVER
Statistics
  • Article View: 258
  • PDF Download: 319

APA

Kadium, A. A., Ali Al Baazi, A. M., & Mahmood, M. M. (2021). Using of calprotectin and lactoferrin levels in early detection of acute uncomplicated appendicitis in children. European Journal of Molecular & Clinical Medicine, 7(1), 4335-4341.

MLA

Athir Ahmed Kadium; Alaa Mohammed Ali Al Baazi; Mahmood Mosa Mahmood. "Using of calprotectin and lactoferrin levels in early detection of acute uncomplicated appendicitis in children". European Journal of Molecular & Clinical Medicine, 7, 1, 2021, 4335-4341.

HARVARD

Kadium, A. A., Ali Al Baazi, A. M., Mahmood, M. M. (2021). 'Using of calprotectin and lactoferrin levels in early detection of acute uncomplicated appendicitis in children', European Journal of Molecular & Clinical Medicine, 7(1), pp. 4335-4341.

VANCOUVER

Kadium, A. A., Ali Al Baazi, A. M., Mahmood, M. M. Using of calprotectin and lactoferrin levels in early detection of acute uncomplicated appendicitis in children. European Journal of Molecular & Clinical Medicine, 2021; 7(1): 4335-4341.

  • Home
  • About Journal
  • Editorial Board
  • Submit Manuscript
  • Contact Us
  • Glossary
  • Sitemap

News

 

For Special Issue Proposal : editor.ejmcm21@gmail.com

Newsletter Subscription

Subscribe to the journal newsletter and receive the latest news and updates

© Journal Management System. Powered by ejournalplus