Anti hepatitis B activity of methanolic extracts of Achyranthes aspera leaves
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 11, Pages 4264-4268
AbstractThe present study aims to investigate the anti hepatitis B activity of Achyranthes aspera. Achyranthes aspera is well known medicinal plant and it is widely distributed in India. Hepatitis B infection is very common disease and it is a major global disease which often leads to liver failure including liver cirrhosis and liver carcinoma. Conventional treatment options are always causes severe post treatment clinical consequences and this limit the use of high does of drugs for treatment. Natural remedies are preferred to combat different diseases and world health organization (WHO) recommends the use of active principles extracted from natural sources as they are well tolerated by human system. In this study we investigated the anti viral efficacy of Achyranthes aspera leaves extract on hepatitis B virus. Different parts of Achyranthes aspera extracts are reported for antimicrobial activities however, there is no reports are available on anti hepatitis B activity Achyranthes aspera collected from Tamil Nadu. In this study Achyranthes aspera leaves extract showed considerable anti hepatitis B activity at different concentration tested. The anti viral activity of A. aspera leaves extract was found to be dose dependent manner and it is comparable with reference drugs.
Key words: Achyranthes aspera; Hepatitis B; Extract; Dose dependent
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